Is it safe for athletes to use anti-inflammatories before and during long endurance races and longer training sessions?

All athletes, from professional athlete to beginners, will need pain medication from time to time. Joints get injured, muscles are strained and “overuse" injuries such as shin splints, plantar fasciitis, and tendonitis are common. Athletes, like their non-athletic counterparts, are not immune to headaches and old-fashioned back pain either. NSAIDs have commonly been used by athletes to treat many conditions including acute musculoskeletal injuries, such as a sprained ankle or muscle soreness after an intense workout. However, athletes are beginning to use these anti-inflammatories to prevent injury or pain, especially before and during long endurance races. It is estimated that 30-50% of participants in Ironman races and marathons take NSAIDs. The theory behind this practice is that the prophylactic inhibition of the production of inflammatory mediators will lead to decreased muscle soreness, fatigue, and ultimately shorter recovery times and improved performance. But is this safe?
What’s the difference between pain medications?
- aspirin and other salicylates
- NSAIDs or “non-steroidal anti-inflammatory drugs” (Ibuprofen and others)
- acetaminophen (Panado and others)
- opiate agonists (morphine, codeine, and others)
Several studies have found little performance benefit from taking ibuprofen and warn that it may mask pain, which can lead to increased risk of injury. Side effects of chronic anti-inflammatory use are well-documented. A common side effect of using NSAIDs is bleeding from the gastrointestinal tract. In a study of gastrointestinal (GI) bleeding in marathon runners, more than half of the applicants had to be excluded because of regular aspirin use (Stewart JG, et al. 1984).
When should you use NSAIDs?
So, with all of these possible side effects and lack of scientific evidence that they help to enhance athletic performance, should one ever take NSAIDs? In general, moderate use after exercise to treat acute musculoskeletal injuries or muscle soreness for a short period of time is usually safe. People who have a history of gastrointestinal bleeding or kidney problems should check with their physicians before taking any NSAIDs. One week should be considered the maximum time frame to self-medicate with a NSAID. Chronic use of NSAIDs should be discouraged, not only to reduce the risk of adverse reactions but also because the condition may require medical attention if it does not resolve within this time period.
Bottom Line
Take care of your body including proper training, rest, nutrition, hydration and recovery. Occasional NSAID use AFTER exercise is probably helpful and safe if used for a short time period for an acute injury. It is probably safer to avoid taking it as an aid to improve athletic performance before or during races. Always seek physician recommendations and expertise if you are ever in doubt about what is best for you.




